diff --git a/arbor-0.9.0-pybind11-3.0.patch b/arbor-0.9.0-pybind11-3.0.patch
new file mode 100644
index 0000000..6fc58db
--- /dev/null
+++ b/arbor-0.9.0-pybind11-3.0.patch
@@ -0,0 +1,22 @@
+diff -Naur arbor-0.9.0-original/python/pyarb.hpp arbor-0.9.0/python/pyarb.hpp
+--- arbor-0.9.0-original/python/pyarb.hpp	2023-08-10 10:47:38.000000000 +0100
++++ arbor-0.9.0/python/pyarb.hpp	2025-11-03 08:24:00.093256311 +0000
+@@ -13,18 +13,6 @@
+ 
+ #include <pybind11/pybind11.h>
+ 
+-// Version check
+-#define mk_tok(x) #x
+-#define mk_ver(M, m, p) mk_tok(M) "." mk_tok(m) "." mk_tok(p)
+-#define PB11_ERR(M, m, p) "Required version of pybind11 is 2.8.1 <= version < 3.0.0 Found " mk_ver(M, m, p)
+-static_assert((PYBIND11_VERSION_HEX >= 0x02080100)
+-              &&
+-              (PYBIND11_VERSION_HEX  < 0x03000000),
+-              PB11_ERR(PYBIND11_VERSION_MAJOR, PYBIND11_VERSION_MINOR, PYBIND11_VERSION_PATCH));
+-#undef PB11_ERR
+-#undef mk_ver
+-#undef mk_tok
+-
+ namespace pyarb {
+ 
+ // Sample recorder object interface.
diff --git a/arbor.spec b/arbor.spec
index ebd3875..8e76de4 100644
--- a/arbor.spec
+++ b/arbor.spec
@@ -49,6 +49,9 @@ Patch:          fix-missing-includes.patch
 # These were eventually included in
 # 76120d16c00ae67128c3c69421ab712f985f3445, along with many other changes.
 Patch:          0001-Fix-a-few-typos-that-cause-failure-to-compile-with-G.patch
+# Remove the hard-coded pybind11 version check so that we can build with
+# pybind11 3.0; this is part of https://github.com/arbor-sim/arbor/pull/2481.
+Patch:          arbor-0.9.0-pybind11-3.0.patch
 
 # Random123 does not support:
 #   mips64r2 mips32r2 s390