diff --git a/python-mmtf.spec b/python-mmtf.spec
index 7ba7b7d..da7d56f 100644
--- a/python-mmtf.spec
+++ b/python-mmtf.spec
@@ -22,7 +22,7 @@ doi: 10.1145/2945292.2945324\
 
 Name: python-mmtf
 Version: 1.1.2
-Release: 14%{?dist}
+Release: 15%{?dist}
 Summary: A decoding library for the macromolecular transmission format (MMTF) 
 License: ASL 2.0
 URL: https://github.com/rcsb/mmtf-python
@@ -38,7 +38,7 @@ BuildRequires: python3-devel
 BuildRequires: python3-setuptools
 %if %{with check}
 BuildRequires: python3-msgpack
-BuildRequires: python3-nose
+BuildRequires: python3-pytest
 BuildRequires: python3-numpy
 %endif
 %{?python_provide:%python_provide python3-mmtf}
@@ -58,7 +58,7 @@ Requires: python3-msgpack
 
 %if %{with check}
 %check
-nosetests-%{python3_version}
+%pytest mmtf/tests/codec_tests.py
 %endif
 
 %files -n python3-mmtf
@@ -68,6 +68,9 @@ nosetests-%{python3_version}
 %{python3_sitelib}/mmtf
 
 %changelog
+* Wed Dec 15 2021 Charalampos Stratakis <cstratak@redhat.com> - 1.1.2-15
+- Use pytest instead of the deprecated nose test runner
+
 * Fri Jul 23 2021 Fedora Release Engineering <releng@fedoraproject.org> - 1.1.2-14
 - Rebuilt for https://fedoraproject.org/wiki/Fedora_35_Mass_Rebuild