diff --git a/.gitignore b/.gitignore
index 08d4b37..e3fee0e 100644
--- a/.gitignore
+++ b/.gitignore
@@ -49,3 +49,9 @@
 /urllib3-2.2.2.tar.gz
 /urllib3-2.2.3.tar.gz
 /urllib3-2.3.0.tar.gz
+/urllib3-2.4.0.tar.gz
+/urllib3-2.5.0.tar.gz
+/urllib3-2.6.0.tar.gz
+/urllib3-2.6.1.tar.gz
+/urllib3-2.6.2.tar.gz
+/urllib3-2.6.3.tar.gz
diff --git a/python-urllib3.rpmlintrc b/python-urllib3.rpmlintrc
index 0b83833..e9bd352 100644
--- a/python-urllib3.rpmlintrc
+++ b/python-urllib3.rpmlintrc
@@ -1,6 +1 @@
-# It is normal that extras metapackages should not have documentation, or any
-# files at all.
-addFilter(r"\+\w+\.\w+: W: no-documentation")
-# Not real spelling errors
-addFilter(r"spelling-error \('([Mm]etapackage)s?',")
 addFilter(r"spelling-error \('(gzip|brotli|zstd)',")
diff --git a/python-urllib3.spec b/python-urllib3.spec
index 999385c..5b863bf 100644
--- a/python-urllib3.spec
+++ b/python-urllib3.spec
@@ -5,7 +5,7 @@
 %bcond extradeps %{undefined rhel}
 
 Name:           python-urllib3
-Version:        2.3.0
+Version:        2.6.3
 Release:        %autorelease
 Summary:        HTTP library with thread-safe connection pooling, file post, and more
 
@@ -20,9 +20,10 @@ Source0:        %{url}/archive/%{version}/urllib3-%{version}.tar.gz
 # Upstream would like to get the necessary changes merged into Hypercorn, but
 # explained clearly why the forked copy is needed for now.
 #
-# Note that dev-requirements.txt references the urllib3-changes branch of
-# https://github.com/urllib3/hypercorn/, and we should use the latest commit
-# from that branch, but we package using a commit hash for reproducibility.
+# Note that tool.uv.sources.hypercorn in pyproject.toml references the
+# urllib3-changes branch of https://github.com/urllib3/hypercorn/, and we
+# should use the latest commit from that branch, but we package using a commit
+# hash for reproducibility.
 #
 # We do not need to treat this as a bundled dependency because it is not
 # installed in the buildroot or otherwise included in any of the binary RPMs.
@@ -33,46 +34,10 @@ Source1:        %{hypercorn_url}/archive/%{hypercorn_commit}/hypercorn-%{hyperco
 BuildArch:      noarch
 
 BuildRequires:  python3-devel
-
+# The conditional is important: we benefit from tomcli for editing dependency
+# groups, but we do not want it when bootstrapping or in RHEL.
 %if %{with tests}
-# Test dependencies are listed only in dev-requirements.txt. Because there are
-# linters and coverage tools mixed in, and exact versions are pinned, we resort
-# to manual listing.
-# h2==4.1.0: also in the h2 extra
-BuildRequires:  %{py3_dist h2}
-# coverage==7.6.4: omitted linter/coverage tool
-# PySocks==1.7.1
-BuildRequires:  %{py3_dist PySocks}
-# pytest==8.0.2
-BuildRequires:  %{py3_dist pytest}
-# pytest-timeout==2.1.0
-BuildRequires:  %{py3_dist pytest-timeout}
-# pyOpenSSL==24.2.1
-BuildRequires:  %{py3_dist pyOpenSSL}
-# idna==3.7
-BuildRequires:  %{py3_dist idna}
-# trustme==1.2.0
-BuildRequires:  %{py3_dist trustme}
-# cryptography==43.0.1
-BuildRequires:  %{py3_dist cryptography}
-# towncrier==23.6.0: used for generating a changelog
-# pytest-memray==1.5.0;python_version<"3.14" and sys_platform!="win32" and
-#     implementation_name=="cpython": not packaged, unwanted profiler
-# trio==0.26.2
-BuildRequires:  %{py3_dist trio}
-# # https://github.com/pallets/quart/pull/369
-# Quart @ git+https://github.com/pallets/quart@67110bf383d8973bce1619e957b4b6ea088ad9f2
-BuildRequires:  %{py3_dist Quart}
-# quart-trio==0.11.1
-BuildRequires:  %{py3_dist quart-trio}
-# # https://github.com/pgjones/hypercorn/issues/62
-# # https://github.com/pgjones/hypercorn/issues/168
-# # https://github.com/pgjones/hypercorn/issues/169
-# hypercorn @ git+https://github.com/urllib3/hypercorn@urllib3-changes
-# hypercorn is packaged, but we need the forked/bundled version
-# httpx==0.25.2
-BuildRequires:  %{py3_dist httpx}
-# pytest-socket==0.7.0: not packaged, not strictly required
+BuildRequires:  tomcli
 %endif
 
 %global _description %{expand:
@@ -138,12 +103,40 @@ Recommends:     python3-urllib3+socks
 recent_date=$(date --date "7 month ago" +"%Y, %_m, %_d")
 sed -i "s/^RECENT_DATE = datetime.date(.*)/RECENT_DATE = datetime.date($recent_date)/" src/urllib3/connection.py
 
+%if %{with tests}
+# Possible improvements to dependency groups
+# https://github.com/urllib3/urllib3/issues/3594
+# Adjust the contents of the "dev" dependency group by removing:
+remove_from_dev() {
+  tomcli set pyproject.toml lists delitem 'dependency-groups.dev' "($1)\b.*"
+}
+#   - Linters, coverage tools, profilers, etc.:
+#     https://docs.fedoraproject.org/en-US/packaging-guidelines/Python/#_linters
+remove_from_dev 'coverage|pytest-memray'
+#   - Dependencies for maintainer tasks
+remove_from_dev 'build|towncrier'
+#   - Dependencies that are not packaged and not strictly required
+remove_from_dev 'pytest-socket'
+#   - Hypercorn, because we have a special forked version we must use for
+#     testing instead, so we do not want to generate a dependency on the system
+#     copy. Note that the system copy is still an indirect dependency via quart
+#     and quart-trio.
+remove_from_dev 'hypercorn'
+
+# Remove all version bounds for test dependencies. We must attempt to make do
+# with what we have. (This also removes any python version or platform
+# constraints, which is currently fine, but could theoretically cause trouble
+# in the future. We’ll cross that bridge if we ever arrive at it.)
+tomcli set pyproject.toml lists replace --type regex_search \
+    'dependency-groups.dev' '[>=]=.*' ''
+%endif
+
 
 %generate_buildrequires
 export SETUPTOOLS_SCM_PRETEND_VERSION='%{version}'
 # Generate BR’s from packaged extras even when tests are disabled, to ensure
 # the extras metapackages are installable if the build succeeds.
-%pyproject_buildrequires %{?with_extradeps:-x brotli,zstd,socks,h2}
+%pyproject_buildrequires %{?with_extradeps:-x brotli,zstd,socks,h2} %{?with_tests:-g dev}
 
 
 %build
diff --git a/sources b/sources
index 6c51285..d7b27ef 100644
--- a/sources
+++ b/sources
@@ -1,2 +1,2 @@
-SHA512 (urllib3-2.3.0.tar.gz) = 7b4b8732f4a4cddb8a6f6854d21febcbecba0762bff65d2291d95d1f54a972c3168f8d7ca1786edfb5c0a0c955cf3812ff6fe1b7925973d3fe31077fbfbdc39c
+SHA512 (urllib3-2.6.3.tar.gz) = 554cedfd97d411fffa9a8ba46f592eab9e58c5fa8822ecd5a73ab45d6adfc188a6b9c4e238d02a4fbd3a1067a25a1de841a33d398d0641e22a32ea414876b615
 SHA512 (hypercorn-d1719f8c1570cbd8e6a3719ffdb14a4d72880abb.tar.gz) = 62d6787d88a2e716f0ac04fc49f6cdc586e473a660ee754ff66961922ae78bcc75d1f78b091e78557dd60f006e8e480114738c7b4ff71beac804e4fc9603240b
diff --git a/tests/smoke/test.py b/tests/smoke/test.py
index d622ddd..9ac5805 100644
--- a/tests/smoke/test.py
+++ b/tests/smoke/test.py
@@ -3,7 +3,6 @@ import urllib3
 http = urllib3.PoolManager()
 r = http.request('GET', 'http://example.com/')
 print('status = {0}'.format(r.status))
-print("headers['server'] = {0}".format(r.headers['server']))
 print(r.data)
 if r.status != 200 or not r.data:
     raise SystemExit(1)