diff --git a/python3.6.spec b/python3.6.spec
index 4721d57..4838fb2 100644
--- a/python3.6.spec
+++ b/python3.6.spec
@@ -231,6 +231,11 @@ License: Python and MIT and ASL 2.0 and BSD and ISC and LGPLv2 and MPLv2.0 and (
 %global wordsize 32
 %endif
 
+# Opt-out from https://fedoraproject.org/wiki/Changes/fno-omit-frame-pointer
+# Python is slower with frame pointers, but we expect to remove this in Python 3.12+
+# See https://lists.fedoraproject.org/archives/list/python-devel@lists.fedoraproject.org/thread/6TQYCHMX4FZLF27U5BCEC7IFV6XNBKJP/
+# Tracking bugzilla: https://bugzilla.redhat.com/2158729
+%undefine _include_frame_pointers
 
 # =======================
 # Build-time requirements