diff --git a/ugene.spec b/ugene.spec
index 828e81d..7332607 100644
--- a/ugene.spec
+++ b/ugene.spec
@@ -50,7 +50,7 @@ Name:		ugene
 Summary:	Integrated bioinformatics toolkit
 
 Version:	%{fedoraver}
-Release:	1%{?dist}
+Release:	2%{?dist}
 
 #The entire source code is GPLv2+ except:
 #file src/libs_3rdparty/qtbindings_core/src/qtscriptconcurrent.h which is GPLv2
@@ -296,6 +296,9 @@ desktop-file-validate %{buildroot}%{_datadir}/applications/%{name}.desktop
 %{_mandir}/man1/%{name}.1*
 
 %changelog
+* Fri Jul 17 2026 Fedora Release Engineering <releng@fedoraproject.org> - 53.1-2
+- Rebuilt for https://fedoraproject.org/wiki/Fedora_45_Mass_Rebuild
+
 * Wed Mar 04 2026 Mamoru TASAKA <mtasaka@fedoraproject.org> - 53.1-1
 - 53.1