diff -uNr a/plugins/python/python_plugin.c b/plugins/python/python_plugin.c
--- a/plugins/python/python_plugin.c	2023-07-27 17:34:12.000000000 +0200
+++ b/plugins/python/python_plugin.c	2023-09-30 18:30:47.884490233 +0200
@@ -197,6 +197,7 @@
 PyMethodDef uwsgi_spit_method[] = { {"uwsgi_spit", py_uwsgi_spit, METH_VARARGS, ""} };
 PyMethodDef uwsgi_write_method[] = { {"uwsgi_write", py_uwsgi_write, METH_VARARGS, ""} };
 
+PyObject *init_uwsgi3(void);
 int uwsgi_python_init() {
 
 	char *pyversion = strchr(Py_GetVersion(), '\n');
@@ -261,6 +262,9 @@
 	wchar_t *pname = uwsgi_calloc(sizeof(wchar_t) * (strlen(program_name)+1));
 	mbstowcs(pname, program_name, strlen(program_name)+1);
 	Py_SetProgramName(pname);
+#ifdef UWSGI_PY312
+	PyImport_AppendInittab("uwsgi", init_uwsgi3);
+#endif
 #else
 	Py_SetProgramName(program_name);
 #endif
@@ -658,7 +662,9 @@
 
 
 #ifdef PYTHREE
+#ifndef UWSGI_PY312
 	PyImport_AppendInittab("uwsgi", init_uwsgi3);
+#endif
 	new_uwsgi_module = PyImport_AddModule("uwsgi");
 #else
 	new_uwsgi_module = Py_InitModule3("uwsgi", NULL, uwsgi_py_doc);
@@ -1161,7 +1167,10 @@
 
 	// prepare for stack suspend/resume
 	if (uwsgi.async > 1) {
-#ifdef UWSGI_PY311
+#ifdef UWSGI_PY312
+		up.current_c_recursion_remaining = uwsgi_malloc(sizeof(int)*uwsgi.async);
+		up.current_py_recursion_remaining = uwsgi_malloc(sizeof(int)*uwsgi.async);
+#elif defined UWSGI_PY311
 		up.current_recursion_remaining = uwsgi_malloc(sizeof(int)*uwsgi.async);
 #else
 		up.current_recursion_depth = uwsgi_malloc(sizeof(int)*uwsgi.async);
@@ -1324,7 +1333,12 @@
 		// Acquire the gil and import lock before forking in order to avoid
 		// deadlocks in workers
 		UWSGI_GET_GIL
+#if defined UWSGI_PY312
+		PyInterpreterState *interp = PyInterpreterState_Get();
+		_PyImport_AcquireLock(interp);
+#else
 		_PyImport_AcquireLock();
+#endif
 	}
 }
 
@@ -1336,7 +1350,12 @@
 	if (uwsgi.has_threads) {
 		if (step == 0) {
 			// Release locks within master process
+#if defined UWSGI_PY312
+			PyInterpreterState *interp = PyInterpreterState_Get();
+			_PyImport_ReleaseLock(interp);
+#else
 			_PyImport_ReleaseLock();
+#endif
 			UWSGI_RELEASE_GIL
 		}
 		else {
@@ -1592,7 +1611,11 @@
 	PyGILState_Release(pgst);
 
 	if (wsgi_req) {
-#ifdef UWSGI_PY311
+#ifdef UWSGI_PY312
+		up.current_c_recursion_remaining[wsgi_req->async_id] = tstate->c_recursion_remaining;
+		up.current_py_recursion_remaining[wsgi_req->async_id] = tstate->py_recursion_remaining;
+		up.current_frame[wsgi_req->async_id] = tstate->cframe;
+#elif defined UWSGI_PY311
 		up.current_recursion_remaining[wsgi_req->async_id] = tstate->recursion_remaining;
 		up.current_frame[wsgi_req->async_id] = tstate->cframe;
 #else
@@ -1601,7 +1624,11 @@
 #endif
 	}
 	else {
-#ifdef UWSGI_PY311
+#ifdef UWSGI_PY312
+		up.current_main_c_recursion_remaining = tstate->c_recursion_remaining;
+		up.current_main_py_recursion_remaining = tstate->py_recursion_remaining;
+		up.current_main_frame = tstate->cframe;
+#elif defined UWSGI_PY311
 		up.current_main_recursion_remaining = tstate->recursion_remaining;
 		up.current_main_frame = tstate->cframe;
 #else
@@ -1835,7 +1862,11 @@
 	PyGILState_Release(pgst);
 
 	if (wsgi_req) {
-#ifdef UWSGI_PY311
+#ifdef UWSGI_PY312
+		tstate->c_recursion_remaining = up.current_c_recursion_remaining[wsgi_req->async_id];
+		tstate->py_recursion_remaining = up.current_py_recursion_remaining[wsgi_req->async_id];
+		tstate->cframe = up.current_frame[wsgi_req->async_id];
+#elif defined UWSGI_PY311
 		tstate->recursion_remaining = up.current_recursion_remaining[wsgi_req->async_id];
 		tstate->cframe = up.current_frame[wsgi_req->async_id];
 #else
@@ -1844,7 +1875,11 @@
 #endif
 	}
 	else {
-#ifdef UWSGI_PY311
+#ifdef UWSGI_PY312
+		tstate->c_recursion_remaining = up.current_main_c_recursion_remaining;
+		tstate->py_recursion_remaining = up.current_main_py_recursion_remaining;
+		tstate->cframe = up.current_main_frame;
+#elif defined UWSGI_PY311
 		tstate->recursion_remaining = up.current_main_recursion_remaining;
 		tstate->cframe = up.current_main_frame;
 #else
diff -uNr a/plugins/python/uwsgi_python.h b/plugins/python/uwsgi_python.h
--- a/plugins/python/uwsgi_python.h	2023-07-27 17:34:12.000000000 +0200
+++ b/plugins/python/uwsgi_python.h	2023-09-30 18:30:24.766699317 +0200
@@ -21,6 +21,10 @@
 #  define UWSGI_PY311
 #endif
 
+#if (PY_VERSION_HEX >= 0x030c0000)
+#  define UWSGI_PY312
+#endif
+
 #if PY_MAJOR_VERSION == 2 && PY_MINOR_VERSION < 7
 #define HAS_NOT_PyMemoryView_FromBuffer
 #endif
@@ -168,7 +172,15 @@
 
 	char *callable;
 
-#ifdef UWSGI_PY311
+#ifdef UWSGI_PY312
+	int *current_c_recursion_remaining;
+	int *current_py_recursion_remaining;
+	_PyCFrame **current_frame;
+
+	int current_main_c_recursion_remaining;
+	int current_main_py_recursion_remaining;
+	_PyCFrame *current_main_frame;
+#elif defined UWSGI_PY311
 	int *current_recursion_remaining;
 	_PyCFrame **current_frame;